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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX16
All Species:
11.52
Human Site:
T111
Identified Species:
19.49
UniProt:
O14662
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14662
NP_001001433.1
325
37031
T111
D
K
H
L
N
R
P
T
L
D
D
S
S
E
E
Chimpanzee
Pan troglodytes
XP_514749
272
31071
I76
I
E
I
T
T
Q
E
I
T
Q
L
F
H
R
C
Rhesus Macaque
Macaca mulatta
XP_001084615
321
36481
L108
K
H
L
N
R
P
T
L
D
D
S
S
E
E
E
Dog
Lupus familis
XP_853504
326
37253
L112
Q
H
L
N
R
P
T
L
D
D
S
S
E
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVI5
326
37034
L112
K
H
L
N
R
P
T
L
D
D
S
S
E
E
E
Rat
Rattus norvegicus
O70257
261
29832
T66
T
N
Q
L
A
K
E
T
D
K
Y
I
K
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511120
304
34831
I108
I
E
I
T
T
Q
E
I
T
Q
L
F
H
R
C
Chicken
Gallus gallus
NP_001006295
326
37263
T112
D
K
H
L
N
R
P
T
L
D
D
S
S
E
E
Frog
Xenopus laevis
NP_001085029
304
35171
I108
I
E
I
A
T
Q
E
I
T
Q
M
F
H
R
C
Zebra Danio
Brachydanio rerio
XP_691316
324
37513
T111
D
K
H
M
N
R
P
T
L
D
D
S
S
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
L96
A
N
R
V
R
G
K
L
K
G
I
E
Q
N
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O16000
291
33234
K96
N
K
V
R
G
K
L
K
L
I
E
N
A
I
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SWH4
323
36414
T108
H
S
K
A
L
M
P
T
F
G
D
N
K
G
I
Baker's Yeast
Sacchar. cerevisiae
Q08144
397
45857
D111
G
F
E
D
K
S
H
D
E
A
L
I
E
D
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.3
97.2
95
N.A.
92.9
27.6
N.A.
82.4
88
78.1
78.7
N.A.
21.5
N.A.
21.5
N.A.
Protein Similarity:
100
83.6
98.1
96.9
N.A.
95.7
46.4
N.A.
88
95.4
88
90.4
N.A.
43
N.A.
41.8
N.A.
P-Site Identity:
100
0
26.6
20
N.A.
26.6
20
N.A.
0
100
0
93.3
N.A.
0
N.A.
13.3
N.A.
P-Site Similarity:
100
13.3
26.6
26.6
N.A.
26.6
26.6
N.A.
13.3
100
13.3
100
N.A.
6.6
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.6
22.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.9
43.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
15
8
0
0
0
0
8
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
22
% C
% Asp:
22
0
0
8
0
0
0
8
29
43
29
0
0
8
8
% D
% Glu:
0
22
8
0
0
0
29
0
8
0
8
8
29
43
43
% E
% Phe:
0
8
0
0
0
0
0
0
8
0
0
22
0
0
8
% F
% Gly:
8
0
0
0
8
8
0
0
0
15
0
0
0
8
0
% G
% His:
8
22
22
0
0
0
8
0
0
0
0
0
22
0
0
% H
% Ile:
22
0
22
0
0
0
0
22
0
8
8
15
0
8
15
% I
% Lys:
15
29
8
0
8
15
8
8
8
8
0
0
15
0
0
% K
% Leu:
0
0
22
22
8
0
8
29
29
0
22
0
0
0
8
% L
% Met:
0
0
0
8
0
8
0
0
0
0
8
0
0
0
0
% M
% Asn:
8
15
0
22
22
0
0
0
0
0
0
15
0
8
0
% N
% Pro:
0
0
0
0
0
22
29
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
8
0
0
22
0
0
0
22
0
0
8
8
0
% Q
% Arg:
0
0
8
8
29
22
0
0
0
0
0
0
0
22
0
% R
% Ser:
0
8
0
0
0
8
0
0
0
0
22
43
22
0
0
% S
% Thr:
8
0
0
15
22
0
22
36
22
0
0
0
0
0
0
% T
% Val:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _